MOR modulator-1
Product Specifications
CAS Number
2976336-81-7
Target
Opioid Receptor
Related Pathways
Neuroscience|||GPCR/G Protein|||Endocrinology/Hormones
Bioactivity
MOR modulator-1 (compound 6) is a potent and selective modulator of the ? opioid receptor (MOR) . Compared to NAT (6?-configuration), MOR modulator-1 demonstrates improved opioid receptor selectivity, enhanced antagonistic effects in vivo, and overall reduced withdrawal symptoms. It connects to the ?, ?, and ? receptors with carboxamide linkers, showing Ki values of 0.25, 41.1, and 1.30 nM respectively.
Smiles
O[C@]12[C@@]34C=5C(O[C@]3([C@@H](NC(=O)C6=NC=CS6)CC1)[H])=C(O)C=CC5C[C@]2(N(CC7CC7)CC4)[H]
Molecular Formula
C24H27N3O4S
Molecular Weight
453.554
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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