CD73-IN-19
Product Specifications
CAS Number
333329-22-9
Target
CD73
Related Pathways
Immunology/Inflammation
Bioactivity
CD73-IN-19 (Compound 4ab) is an inhibitor of CD73, demonstrating a 44% inhibition rate of CD73 enzyme activity at 100 μM. It entirely counters T cell proliferation blockade triggered by TCR activation (induced by CD73 activity) at 10 μM and 100 μM and inhibits hA2A receptor activity in HEK-293 cells with a Ki of 3.31 μM. CD73-IN-19 holds potential for research in the field of immune diseases.
Smiles
O=C(OC)C1=CC=C(C=C1)NC(=O)C=2SC3=NC(=CC(=C3C2N)C)C
Molecular Formula
C18H17N3O3S
Molecular Weight
355.411
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP2-97892IR 0.1 mL
Rabbit Polyclonal TEM7/PLXDC1 Antibody [DyLight 755]
Sign In for Pricing
View Details K3353108 1.0 µg DNA
Crybb3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details E16FMB090.1-500U 500 µg
Biotin anti-rat CD90/mouse CD90.1 (Thy-1.1)
Sign In for Pricing
View Details