PRMT5-IN-47
Product Specifications
CAS Number
3065081-87-7
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
PRMT5-IN-47 (compound 20) is a potent, selective, and orally active MTA co-operative PRMT5 inhibitor, with an IC50 value of 15 nM. It exhibits antiproliferative and anticancer activity.
Smiles
C(N(C)[C@H]1CN(CC1)C2=CC=C(C#N)C=C2)(=O)C=3C=C4C5=C(C(N)=NC4=CC3F)COC5
Molecular Formula
C24H22FN5O2
Molecular Weight
431.462
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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