PROTAC JNK1-targeted-1
Product Specifications
Target
JNK, PROTACs
Related Pathways
PROTAC, MAPK
Bioactivity
PROTAC JNK1-targeted-1 (PA2) is a JNK1 PROTAC degrader with a DC50 of 10 nM. It effectively reduces fibronectin levels and is useful in lung fibrosis research. [Pink: JNK1 inhibitor; Black: linker; Blue: CRBN Ligand]
Smiles
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCCCNC(=O)C4=CC=C(C=C4)NC5=NC=C(C(=N5)NC6=CC=CC=C6C(=O)N)Br
Molecular Formula
C35H32BrN9O6
Molecular Weight
754.589
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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