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IPS-06061

Product Specifications

Target

Ras, Molecular Glues

Related Pathways

GPCR/G Protein, PROTAC, MAPK

Bioactivity

IPS-06061 is an orally active molecular glue that forms a ternary complex with CRBN and KRASG12D, capable of degrading KRAS G12D, with a DC50 of less than 500 nM.

Smiles

CCOC(=O)[C@H](CCC1=CC=CC=C1)C[C@@H](C)C(=O)C2=CC=CC=C2

Molecular Formula

C22H26O3

Molecular Weight

338.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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