JNJ-47117096

1610586-62-3

FLT|||MELK

PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

JNJ-47117096 is a potent and selective MELK inhibitor with an IC50 of 23 nM, and it also exhibits strong activity against Flt3 with an IC50 of 18 nM.

O=C(NC1=CC=C2C(=C1)CCNCC2)C=3C=CC(=CC3OC)C=4C=NNC4

C21H22N4O2

362.425

Cool pack

-20°C

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