What is the catalog number for EGFR-IN-144?

The catalog number for EGFR-IN-144 is T204605.

What sizes are available for EGFR-IN-144?

EGFR-IN-144 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR-IN-144 come in?

EGFR-IN-144 is available in 2 different pack sizes.

Is EGFR-IN-144 in stock?

EGFR-IN-144 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR-IN-144?

EGFR-IN-144 is manufactured by Molfinity.

What is the estimated delivery time for EGFR-IN-144?

Estimated delivery time for EGFR-IN-144 is approximately 10 business day(s), depending on your location.

EGFR-IN-144

Product Specifications

Target

Microtubule Associated, Interleukin, Apoptosis, EGFR, TNF

Related Pathways

Tyrosine Kinase/Adaptors, Apoptosis, Immunology/Inflammation, Angiogenesis, JAK/STAT signaling, Cytoskeletal Signaling

Bioactivity

EGFR-IN-144 (Compound 4B) inhibits EGFR (IC50=0.639 μg/mL) and tubulin polymerization (IC50=7.339 μg/mL) . It exhibits cytotoxicity in various cancer cells with a GI50 at the nanomolar level. EGFR-IN-144 reduces the expression of mTOR, TNF-α, and IL-6, causes G1/S phase cell cycle arrest, and induces apoptosis.