MTHFD2-IN-5
Product Specifications
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
MTHFD2-IN-5 (Compound 16e) is a selective inhibitor of MTHFD2 with an IC50 of 66 nM. It inhibits the proliferation of MOLM-14 cells with a GI50 of 720 nM and demonstrates antitumor activity in mouse models.
Smiles
C1=CC(=C(C=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)Cl)NC(=O)NC2=C(N=C(NC2=O)N)N
Molecular Formula
C17H18ClN7O7
Molecular Weight
467.821
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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