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SBI-810 hydrochloride

Product Specifications

CAS Number

2772746-58-2

Target

Neurotensin Receptor, NMDAR, ERK, Sodium Channel

Related Pathways

Membrane transporter/Ion channel, GPCR/G Protein, Neuroscience, MAPK

Purity

0.9942

Bioactivity

SBI-810 hydrochloride is a β-arrestin-2 (βarr2) -biased allosteric modulator of NTSR1 (neurotensin receptor 1), exerting analgesic effects through peripheral and central mechanisms by inhibiting excitatory synaptic transmission, suppressing NMDA receptor and ERK signalling in spinal nociceptive neurons, and reducing Nav1.7 expression and action potential discharge in primary sensory neurons.

Smiles

Cl.OCCN(C=1C=CC=2N=C(N=C(C2C1)N3CCC(C=4C=CC=CC4OC)CC3)C5(C)CC5)C

Molecular Formula

C27H35ClN4O2

Molecular Weight

483.05

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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