SBI-810 hydrochloride
Product Specifications
CAS Number
2772746-58-2
Target
Neurotensin Receptor, NMDAR, ERK, Sodium Channel
Related Pathways
Membrane transporter/Ion channel, GPCR/G Protein, Neuroscience, MAPK
Purity
0.9942
Bioactivity
SBI-810 hydrochloride is a β-arrestin-2 (βarr2) -biased allosteric modulator of NTSR1 (neurotensin receptor 1), exerting analgesic effects through peripheral and central mechanisms by inhibiting excitatory synaptic transmission, suppressing NMDA receptor and ERK signalling in spinal nociceptive neurons, and reducing Nav1.7 expression and action potential discharge in primary sensory neurons.
Smiles
Cl.OCCN(C=1C=CC=2N=C(N=C(C2C1)N3CCC(C=4C=CC=CC4OC)CC3)C5(C)CC5)C
Molecular Formula
C27H35ClN4O2
Molecular Weight
483.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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