FUT8-IN-1
Product Specifications
Target
Transferase
Related Pathways
Metabolism
Bioactivity
FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 μM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.
Smiles
CCN1CCN(C(C1)C2=CC=CC=C2)CC3=C(C=CC4=C3C=CC(=C4)Cl)O
Molecular Formula
C23H25ClN2O
Molecular Weight
380.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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