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MAT2A-IN-21

Product Specifications

CAS Number

3062073-94-0

Target

Methionine Adenosyltransferase (MAT)

Related Pathways

Chromatin/Epigenetic

Bioactivity

MAT2A-IN-21 (compound 28) is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A), with an IC50 of 49 nM. It selectively inhibits cancer cells with MTAP deficiency.

Smiles

O=C1C(=NC=2C=CC(=CC2N1C3=CC=C(OC(F)F)C=C3)C4CC4)C=5C=CC=6N=CN(C6C5)C

Molecular Formula

C26H20F2N4O2

Molecular Weight

458.459

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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