MAT2A-IN-21
Product Specifications
CAS Number
3062073-94-0
Target
Methionine Adenosyltransferase (MAT)
Related Pathways
Chromatin/Epigenetic
Bioactivity
MAT2A-IN-21 (compound 28) is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A), with an IC50 of 49 nM. It selectively inhibits cancer cells with MTAP deficiency.
Smiles
O=C1C(=NC=2C=CC(=CC2N1C3=CC=C(OC(F)F)C=C3)C4CC4)C=5C=CC=6N=CN(C6C5)C
Molecular Formula
C26H20F2N4O2
Molecular Weight
458.459
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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