CDK4/6-IN-23
Product Specifications
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CDK4/6-IN-23 (Compound 42) is a potent and selective inhibitor of CDK4/6, displaying an IC50 of 11 nM for CDK6. This compound significantly activates immune cells and enhances IL-3 production. In mice undergoing 5-FU chemotherapy, CDK4/6-IN-23 demonstrates dual bone marrow protection and immunomodulatory effects.
Smiles
CC(=O)N1CCC2(CC1)CC(=O)C3=C(O2)C=C(C=C3)C4=NC(=NC=C4F)NC5=NC=C(C=C5)N6CCN(CC6)C(=O)C7CC7
Molecular Formula
C32H34FN7O4
Molecular Weight
599.655
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/315447026508628001/T204550
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6170563-01 0.1 mL
STAT2 (Signal Transducer and Activator of Transcription 2, 113kD, ISGF-3, MGC59816, P113, STAT113) (Biotin)
Ask
View Details MBS6170563-02 5x 0.1 mL
STAT2 (Signal Transducer and Activator of Transcription 2, 113kD, ISGF-3, MGC59816, P113, STAT113) (Biotin)
Ask
View Details