What is the catalog number for SIRT6-IN-4?

The catalog number for SIRT6-IN-4 is T204538.

What sizes are available for SIRT6-IN-4?

SIRT6-IN-4 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does SIRT6-IN-4 come in?

SIRT6-IN-4 is available in 2 different pack sizes.

Is SIRT6-IN-4 in stock?

SIRT6-IN-4 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SIRT6-IN-4?

SIRT6-IN-4 is manufactured by Molfinity.

What is the estimated delivery time for SIRT6-IN-4?

Estimated delivery time for SIRT6-IN-4 is approximately 10 business day(s), depending on your location.

SIRT6-IN-4

Product Specifications

Target

Sirtuin, Apoptosis

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis

Bioactivity

SIRT6-IN-4 (Compound 10d) is a selective inhibitor of SIRT6 with an IC50 of 5.68 μM. It inhibits the proliferation of MCF-7 cells, with an IC50 of 8.30 μM, and causes cell cycle arrest at the G2/M phase. Additionally, SIRT6-IN-4 impedes cell migration and invasion of MCF-7 and induces apoptosis. In mouse models, this compound exhibits antitumor activity.