ELP-004
Product Specifications
CAS Number
15533-81-0
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ELP-004 is a TRPC channel inhibitor that blocks Ca2+ entry mediated by TRPC channels. It serves as an osteoclast inhibitor by preventing osteoclast differentiation. ELP-004 also hinders basal Ca2+ levels and the associated translocation of NFATc1 in inflammatory osteoclastogenesis. Additionally, it reduces bone erosion in mouse models of rheumatoid arthritis.
Smiles
O=C(N(C1=CC=C(Cl)C(Cl)=C1)C)CC
Molecular Formula
C10H11Cl2NO
Molecular Weight
232.106
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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