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HPK1-IN-55

Product Specifications

CAS Number

3048537-58-9

Target

MAPK

Related Pathways

MAPK

Bioactivity

HPK1-IN-55 (compound 19) is a selective and orally active inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of less than 0.51 nM. It exhibits exceptional kinase selectivity, being over 637 times more selective for HPK1 compared to GCK kinase and over 1022 times compared to LCK. HPK1-IN-55 possesses anti-cancer properties.

Smiles

O=C(N)C1=NC(=C(OC)C=C1NC=2N=C3C(=CC2)C4(N(C)C3)CCN(CC4)C5COC5)C6=CC=CC7=C6N=CN7C

Molecular Formula

C30H34N8O3

Molecular Weight

554.643

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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