DALK-3
Product Specifications
Target
ALK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
DALK-3 is a degrader of anaplastic lymphoma kinase (ALK) that effectively induces the degradation of EML4-ALK with a DC50 of 0.182 μM. It exhibits significant antiproliferative activity against H3122 cells and is applicable for tumor research.
Smiles
COC1=CC=C(C=C1)C(=O)/C=C/C(=O)N2CCN(CC2)C3CCN(CC3)C4=CC(=C(C=C4)NC5=NC=C(C(=N5)NC6=CC=CC=C6P(=O)(C)C)Cl)OC
Molecular Formula
C39H45ClN7O5P
Molecular Weight
758.245
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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