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DALK-3

Product Specifications

Target

ALK

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

DALK-3 is a degrader of anaplastic lymphoma kinase (ALK) that effectively induces the degradation of EML4-ALK with a DC50 of 0.182 μM. It exhibits significant antiproliferative activity against H3122 cells and is applicable for tumor research.

Smiles

COC1=CC=C(C=C1)C(=O)/C=C/C(=O)N2CCN(CC2)C3CCN(CC3)C4=CC(=C(C=C4)NC5=NC=C(C(=N5)NC6=CC=CC=C6P(=O)(C)C)Cl)OC

Molecular Formula

C39H45ClN7O5P

Molecular Weight

758.245

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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