BJP-07-017-3
Product Specifications
CAS Number
2468783-22-2
Target
Others
Related Pathways
Others
Bioactivity
BJP-07-017-3 is an inhibitor of proline cis-trans isomerase (Pin1) with an IC50 of 9 nM. It forms a covalent bond with Cys113 of Pin1, inducing conformational changes that decrease its stability and lead to proteasome-dependent degradation.
Smiles
C([C@H](NC(=O)[C@H]1N(C([C@H](CC2=CC=CC=C2)N(C(CCl)=O)C)=O)CCCC1)C(N[C@@H](CCCNC(N)=O)C(N)=O)=O)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C35H45ClN8O6
Molecular Weight
709.235
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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