MTH1 activator-1
Product Specifications
CAS Number
2803422-60-6
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.
Smiles
O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCOCC2)C3=NC=C(C#CC4=CC=CC=5C=NC=CC45)C=C3
Molecular Formula
C29H23F3N4O2
Molecular Weight
516.514
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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