MLK3-IN-1
Product Specifications
Target
FAK, MLK
Related Pathways
Cytoskeletal Signaling, Angiogenesis, MAPK, Tyrosine Kinase/Adaptors
Bioactivity
MLK3-IN-1 (Compound 37) is a selective inhibitor of mixed-lineage kinase 3 (MLK3) with an IC50 of less than 1 nM. It also inhibits FAK with an IC50 of 15.5 μM. In both murine and human liver microsomes, MLK3-IN-1 demonstrates excellent metabolic stability.
Smiles
CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC=C(C=C3)C(F)(F)F
Molecular Formula
C20H16F6N4O2S
Molecular Weight
490.422
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15376457 1 Vial
Lentiviral human DENND6B sgRNA gene knockout kit - Lentiviral human DENND6B sgRNA gene knockout kit (plasmid)
Sign In for Pricing
View Details 
GTR15372520 1 Vial
Lentiviral human LACTB2 sgRNA gene knockout kit - Lentiviral human LACTB2 sgRNA gene knockout kit (100)
Sign In for Pricing
View Details 
GTR15144442 1 Vial
Lentiviral human PGAM2 shRNA (UAS) - Lentiviral human PGAM2 shRNA (UAS, GFP) plasmid
Sign In for Pricing
View Details E45H04149-2 20 µg
GTP cyclohydrolase 1 (GCH1) (NM_001024024) Human Over-expression Lysate
Sign In for Pricing
View Details