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TMX-2039

Product Specifications

CAS Number

2488892-01-7

Target

Ligands for Target Protein for PROTAC, CDK

Related Pathways

PROTAC, Cell Cycle/Checkpoint

Bioactivity

TMX-2039 is a pan-CDK inhibitor that targets cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcription CDKs (CDK7 and CDK9), with IC50 values of 2.6, 1.0, 52.1, 0.5, 35.0, 32.5, and 25 nM, respectively. It serves as a ligand for the target protein in PROTAC applications.

Smiles

O=C(N)C=1C(F)=CC=CC1NC2=NC(=NC=C2Br)NC3CCN(CC3)S(=O)(=O)C

Molecular Formula

C17H20BrFN6O3S

Molecular Weight

487.347

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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