TMX-2039
Product Specifications
CAS Number
2488892-01-7
Target
Ligands for Target Protein for PROTAC|||CDK
Related Pathways
PROTAC|||Cell Cycle/Checkpoint
Bioactivity
TMX-2039 is a pan-CDK inhibitor that targets cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcription CDKs (CDK7 and CDK9), with IC50 values of 2.6, 1.0, 52.1, 0.5, 35.0, 32.5, and 25 nM, respectively. It serves as a ligand for the target protein in PROTAC applications.
Smiles
O=C(N)C=1C(F)=CC=CC1NC2=NC(=NC=C2Br)NC3CCN(CC3)S(=O)(=O)C
Molecular Formula
C17H20BrFN6O3S
Molecular Weight
487.347
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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