RIPK1-IN-28
Product Specifications
CAS Number
2968509-28-4
Target
RIP kinase
Related Pathways
NF-κB, Apoptosis
Bioactivity
RIPK1-IN-28 (compound 13) is an orally active inhibitor of RIPK1. It exhibits inhibitory effects on human I2.1 and Hepa1-6 cells, with IC50 values of 0.4 and 1.2 nM, respectively.
Smiles
CN1C=2C(OC[C@H](NC(=O)C3=NN(C(C)=CC3=O)C4=CC=CC=C4)C1=O)=CC=C(C#CC5CC5)C2
Molecular Formula
C27H24N4O4
Molecular Weight
468.504
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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