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AZ14240475

Product Specifications

Target

EGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

Bioactivity

AZ14240475 is a potent, selective, brain-penetrant inhibitor of EGFREx20Ins mutants (EGFREx20Ins mutants) with a pIC50 of 7.6, playing a significant role in cancer research.

Smiles

C=CC(=O)N1CC2=C(C1)N(C(=N2)C3=CC(=C(C=C3F)F)OC4=NC=CC(=C4)Cl)C5=NC=NC=C5

Molecular Formula

C23H15ClF2N6O2

Molecular Weight

480.854

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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