AZ14240475
Product Specifications
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
AZ14240475 is a potent, selective, brain-penetrant inhibitor of EGFREx20Ins mutants (EGFREx20Ins mutants) with a pIC50 of 7.6, playing a significant role in cancer research.
Smiles
C=CC(=O)N1CC2=C(C1)N(C(=N2)C3=CC(=C(C=C3F)F)OC4=NC=CC(=C4)Cl)C5=NC=NC=C5
Molecular Formula
C23H15ClF2N6O2
Molecular Weight
480.854
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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