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α-Glucosidase-IN-79

Product Specifications

Target

Glycosidase

Related Pathways

Metabolism

Bioactivity

α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-glucosidase inhibitor with an IC50 of 2.11 μM, demonstrating greater inhibitory potency than the existing α-glucosidase inhibitors Acarbose (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM) . It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research in type 2 diabetes.

Smiles

CC1CCC2=C(C1)SC(=C2C#N)NC(=O)COC3=CC(=CC(=C3OC)OC)C=O

Molecular Formula

C21H22N2O5S

Molecular Weight

414.475

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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