VEGFR-2-IN-63
Product Specifications
Target
VEGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
VEGFR-2-IN-63 (Compound 12b) is an inhibitor of VEGFR2, reducing 87.2% of VEGFR-2 activity at 10 μM. It exhibits anti-proliferative activity against various cancer cells, with IC50 values of 6.5 μM for HCT116, 2.1 μM for MCF7, and 4.1 μM for PaCa2.
Smiles
C1=CC=C(C=C1)NC(=O)NC2=CC=C(C=C2)C(=O)/C=C/3\C4=CC=CC=C4NC3=O
Molecular Formula
C23H17N3O3
Molecular Weight
383.399
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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