P2X4 antagonist-4
Product Specifications
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 μM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1β.
Smiles
CC1=C(C=CC(=C1)F)CS(=O)(=O)NC2=CC=C(C=C2)N3C(=O)CC(=O)NC4=C3C=CC5=CC=CC=C54
Molecular Formula
C27H22FN3O4S
Molecular Weight
503.545
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6241600-02 5x 0.1 mL
CD31 (PECAM-1, Platelet gpIIa Molecule) (AP)
Sign In for Pricing
View Details 
12160151 3x 1.0 µg DNA
APOA5 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Sign In for Pricing
View Details 