P2X4 antagonist-4
Product Specifications
Target
P2X Receptor
Related Pathways
Neuroscience|||Membrane transporter/Ion channel
Bioactivity
P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1?.
Smiles
CC1=C(C=CC(=C1)F)CS(=O)(=O)NC2=CC=C(C=C2)N3C(=O)CC(=O)NC4=C3C=CC5=CC=CC=C54
Molecular Formula
C27H22FN3O4S
Molecular Weight
503.545
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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