P2X4 antagonist-4

Product Specifications

Target

P2X Receptor

Related Pathways

Neuroscience|||Membrane transporter/Ion channel

Bioactivity

P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1?.

Smiles

CC1=C(C=CC(=C1)F)CS(=O)(=O)NC2=CC=C(C=C2)N3C(=O)CC(=O)NC4=C3C=CC5=CC=CC=C54

Molecular Formula

C27H22FN3O4S

Molecular Weight

503.545

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RG227719 10 µg

LAX1 (NM_001136190) Human Tagged ORF Clone

Ask

View Details

Z04329-100 100 µg

CD79B, His, Mouse

Ask

View Details

NBP3-05998MFV500 0.1 mL

Mouse Monoclonal EBOV GP Antibody (02) [mFluor Violet 500 SE]

Ask

View Details

RC222453L2V 200 µL

ADAM9 (NM_003816) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

MBS9213016-01 0.08 mL

Ethanolamine Kinase (EKI1) Antibody (N-term)

Ask

View Details

MBS9213016-02 0.4 mL

Ethanolamine Kinase (EKI1) Antibody (N-term)

Ask

View Details