What is the catalog number for DNA ligase-IN-2?

The catalog number for DNA ligase-IN-2 is T204415.

What sizes are available for DNA ligase-IN-2?

DNA ligase-IN-2 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does DNA ligase-IN-2 come in?

DNA ligase-IN-2 is available in 2 different pack sizes.

Is DNA ligase-IN-2 in stock?

DNA ligase-IN-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DNA ligase-IN-2?

DNA ligase-IN-2 is manufactured by Molfinity.

What is the estimated delivery time for DNA ligase-IN-2?

Estimated delivery time for DNA ligase-IN-2 is approximately 10 business day(s), depending on your location.

DNA ligase-IN-2

Product Specifications

CAS Number

635681-64-0

Target

DNA/RNA Synthesis, Antibacterial

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology

Bioactivity

DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.