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PPAR?/? modulator 2

Product Specifications

Target

PPAR

Related Pathways

Metabolism|||DNA Damage/DNA Repair

Bioactivity

PPAR?/? modulator 2 (Compound 3h) functions as a PPAR? agonist and a PPAR? antagonist, with Ki values for PPAR? and PPAR? of 2.8 ?M and 43 nM, respectively. It significantly enhances adiponectin production and promotes adipogenic differentiation in human bone marrow-derived mesenchymal stem cells (hBM-MSCs) . This compound is applicable in research on metabolic diseases related to hypoadiponectinemia.

Smiles

C1[C@@H](C([C@@H]([Se]1)CN2C=NC3=C(N=C(N=C32)Cl)NCC4=CC(=CC=C4)I)O)O

Molecular Formula

C17H17ClIN5O2Se

Molecular Weight

564.67

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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