What is the catalog number for P53 Activator 14?

The catalog number for P53 Activator 14 is T204386.

What sizes are available for P53 Activator 14?

P53 Activator 14 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does P53 Activator 14 come in?

P53 Activator 14 is available in 2 different pack sizes.

Is P53 Activator 14 in stock?

P53 Activator 14 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P53 Activator 14?

P53 Activator 14 is manufactured by Molfinity.

What is the estimated delivery time for P53 Activator 14?

Estimated delivery time for P53 Activator 14 is approximately 10 business day(s), depending on your location.

P53 Activator 14

Product Specifications

CAS Number

2922588-44-9

Target

Apoptosis, MDM-2/p53

Related Pathways

Apoptosis

Bioactivity

P53 Activator 14 (Compound 7A) is a derivative of Neratinib that can induce DNA damage and activate p53, thereby inhibiting the proliferation of various cancer cells, with an IC50 of 7.21 μM for HCT116 cells. This compound hinders adhesion, migration, and invasion of HCT116 cells, disrupts the cell cycle, and triggers apoptosis. In addition, p53 Activator 14 exhibits anti-tumor properties and inhibits angiogenesis in the chick embryo chorioallantoic membrane (CAM) model.