PKM2-IN-8
Product Specifications
Target
Apoptosis, PKM
Related Pathways
Metabolism, Apoptosis
Bioactivity
PKM2-IN-8 (Compound 9b) is an inhibitor of pyruvate kinase M2 (PKM2) with an IC50 of 0.31 μM. It exhibits potent antiproliferative activity against U87MG glioma cells. PKM2-IN-8 induces early apoptosis and reduces lactate levels. This compound is useful for research in glioblastoma.
Smiles
C1=CC=C2C=C(C=CC2=C1)C3=NN(N=N3)CC(=O)C4=CN=C5N4C=CC=N5
Molecular Formula
C19H13N7O
Molecular Weight
355.353
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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