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PKM2-IN-8

Product Specifications

Target

Apoptosis, PKM

Related Pathways

Metabolism, Apoptosis

Bioactivity

PKM2-IN-8 (Compound 9b) is an inhibitor of pyruvate kinase M2 (PKM2) with an IC50 of 0.31 μM. It exhibits potent antiproliferative activity against U87MG glioma cells. PKM2-IN-8 induces early apoptosis and reduces lactate levels. This compound is useful for research in glioblastoma.

Smiles

C1=CC=C2C=C(C=CC2=C1)C3=NN(N=N3)CC(=O)C4=CN=C5N4C=CC=N5

Molecular Formula

C19H13N7O

Molecular Weight

355.353

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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