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SHO1122147

Product Specifications

Target

Mitochondrial Metabolism

Related Pathways

Metabolism

Bioactivity

SHO1122147 (Compound 7m) disrupts the mitochondrial electron transport chain, demonstrating mitochondrial uncoupling activity (EC50=3.6 μM) . It increases the cellular oxygen consumption rate (OCR=69%) and enhances cellular respiration. Additionally, SHO1122147 is orally active and can be utilized in research related to obesity and metabolic dysfunction-associated steatohepatitis (MASH) .

Smiles

C1=CC(=CC(=C1)Cl)C2=CC=C(C=C2)NC3=CNC4=NON=C4C3=O

Molecular Formula

C17H11ClN4O2

Molecular Weight

338.748

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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