SHO1122147
Product Specifications
Target
Mitochondrial Metabolism
Related Pathways
Metabolism
Bioactivity
SHO1122147 (Compound 7m) disrupts the mitochondrial electron transport chain, demonstrating mitochondrial uncoupling activity (EC50=3.6 ?M) . It increases the cellular oxygen consumption rate (OCR=69%) and enhances cellular respiration. Additionally, SHO1122147 is orally active and can be utilized in research related to obesity and metabolic dysfunction-associated steatohepatitis (MASH) .
Smiles
C1=CC(=CC(=C1)Cl)C2=CC=C(C=C2)NC3=CNC4=NON=C4C3=O
Molecular Formula
C17H11ClN4O2
Molecular Weight
338.748
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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