Sulfo Cy5-tetrazine sodium

Sulfo Cy5-tetrazine sodium is a Cy5 derivative dye with properties similar to CY5, featuring fluorescence characteristics (Ex/Em=633/647 nm) . It acts as a click chemistry reagent, incorporating a Tetrazine group that can engage in an inverse electron-demand Diels-Alder reaction (iEDDA) with molecules containing a TCO group.

CC1=NN=C(N=N1)C2=CC=C(C=C2)CNC(=O)CCCCC[N+]3=C(C(C4=C3C=CC5=C4C=CC(=C5)S(=O)(=O)O)(C)C)/C=C/C=C/C=C/6\C(C7=C(N6CCCCS(=O)(=O)[O-])C=CC8=C7C=CC(=C8)S(=O)(=O)[O-])(C)C.[Na+]