PFK-IN-1
Product Specifications
CAS Number
735303-62-5
Target
Parasite
Related Pathways
Microbiology/Virology
Bioactivity
PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.
Smiles
O=C(NC1=CC=C(C=C1)S(=O)(=O)NC2=NOC(=C2)C)CC3=CC=C(Cl)C(Cl)=C3
Molecular Formula
C18H15Cl2N3O4S
Molecular Weight
440.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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