DNA gyrase/Topo IV-IN-1
Product Specifications
Target
Antibiotic, Topoisomerase, Antibacterial
Related Pathways
Microbiology/Virology, DNA Damage/DNA Repair
Bioactivity
DNA gyrase/Topo IV-IN-1 (Compound 27) is an inhibitor of DNA gyrase and topoisomerase IV with antibacterial properties. It exhibits IC50 values of 11 and 17 nM against the DNA gyrase of Escherichia coli and methicillin-resistant Staphylococcus aureus, respectively, and IC50 values of 83 and 21 nM against topoisomerase IV of the same organisms. DNA gyrase/Topo IV-IN-1 is applicable in anti-infective research.
Smiles
CC(C)[C@H]1C2=C(C(=C3C(=C2OCCN4CCCC4)[C@H](C5=C(O3)C(C(=O)C(C5=O)(C)C)(C)C)C(C)C)C(=O)C(C)C)OC6=C1C(=O)C(C(=O)C6(C)C)(C)C
Molecular Formula
C44H59NO8
Molecular Weight
729.941
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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