FSH receptor antagonist 1
Product Specifications
CAS Number
487064-35-7
Target
Estrogen Receptor/ERR
Related Pathways
Endocrinology/Hormones
Bioactivity
FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G (s) protein-coupled human follicle-stimulating hormone (FSH) receptor. It exhibits an IC50 value of 28 nM in cell lines expressing the human FSH receptor. This compound significantly inhibits follicle growth and ovulation in in vitro mouse models.
Smiles
O=C(NC1=CC=C2C(=C1)C(C=3C=CC=CC3)(C)CC(N2C(=O)C)(C)C)C=4C=CC(=CC4)C=5C=CC=CC5
Molecular Formula
C33H32N2O2
Molecular Weight
488.619
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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