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Thalidomide-O-CH2-CO-NH-C2-PEG2-NH-Boc

Product Specifications

CAS Number

1957235-73-2

Target

E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC

Bioactivity

Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc is a conjugate combining an E3 ligase ligand with a linker, featuring a Thalidomide-based CEREBLON ligand and a PEG linker. It serves as a component in the synthesis of the PROTAC degrader JB300.

Smiles

O=C(OC(C)(C)C)NCCOCCOCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

Molecular Formula

C26H34N4O10

Molecular Weight

562.569

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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