Thalidomide-O-CH2-CO-NH-C2-PEG2-NH-Boc
Product Specifications
CAS Number
1957235-73-2
Target
E3 Ligase Ligand-Linker Conjugate
Related Pathways
PROTAC
Bioactivity
Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc is a conjugate combining an E3 ligase ligand with a linker, featuring a Thalidomide-based CEREBLON ligand and a PEG linker. It serves as a component in the synthesis of the PROTAC degrader JB300.
Smiles
O=C(OC(C)(C)C)NCCOCCOCCNC(=O)COC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
Molecular Formula
C26H34N4O10
Molecular Weight
562.569
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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