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SARS-CoV-2-IN-107

Product Specifications

Target

SARS-CoV, Virus Protease, NO Synthase

Related Pathways

Microbiology/Virology, Immunology/Inflammation

Bioactivity

SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.

Smiles

C1=CC(=CC=C1C(=O)/C=C/C2=CC(=C(C(=C2)O)O)O)F

Molecular Formula

C15H11FO4

Molecular Weight

274.244

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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