SARS-CoV-2-IN-107
Product Specifications
Target
SARS-CoV, Virus Protease, NO Synthase
Related Pathways
Microbiology/Virology, Immunology/Inflammation
Bioactivity
SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.
Smiles
C1=CC(=CC=C1C(=O)/C=C/C2=CC(=C(C(=C2)O)O)O)F
Molecular Formula
C15H11FO4
Molecular Weight
274.244
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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