CG-3-246
Product Specifications
Target
Bcl-2 Family|||FLT
Related Pathways
Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
CG-3-246 is a dual inhibitor targeting FLT3 and BCL-2, with dissociation constants (Kd) of 63 nM and 4.25 nM, respectively. This compound plays a significant role in acute myeloid leukemia research.
Smiles
CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCN(CC3)C(=O)CNC4=C(C=C(C=C4)S(=O)(=O)NC(=O)C5=C(C=C(C=C5)N6CCN(CC6)CC7=C(CC(CC7)(C)C)C8=CC=C(C=C8)Cl)OC9=CN=C1C(=C9)C=CN1)[N+](=O)[O-])OC)NC1CCOCC1
Molecular Formula
C64H73ClN14O10S
Molecular Weight
1265.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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