VEGFR-2-IN-64
Product Specifications
Target
Apoptosis|||VEGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Apoptosis|||Angiogenesis
Bioactivity
VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC50 of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells.
Smiles
CCCCCCCCCCCCCCCCCCN1C=C(N=N1)COC(=O)C2=CC(=CC(=C2)C(=O)OCC3=CN(N=N3)CCCCCCCCCCCCCCCCCC)C(=O)OCC4=CN(N=N4)CCCCCCCCCCCCCCCCCC
Molecular Formula
C72H123N9O6
Molecular Weight
1210.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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