What is the catalog number for Purinostat?

The catalog number for Purinostat is T204269.

What sizes are available for Purinostat?

Purinostat is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Purinostat come in?

Purinostat is available in 2 different pack sizes.

Is Purinostat in stock?

Purinostat is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Purinostat?

Purinostat is manufactured by Molfinity.

What is the estimated delivery time for Purinostat?

Estimated delivery time for Purinostat is approximately 10 business day(s), depending on your location.

Purinostat

Product Specifications

CAS Number

1929583-17-4

Target

HDAC

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

Purinostat is a selective inhibitor of HDACI/IIb with potential anti-leukemic properties. Its mesylate form, Purinostat mesylate, is effective at inhibiting the survival of Ph+ leukemic cells and CD34+ leukemic cells derived from CML patients. Purinostat mesylate targets HDACI/IIb, impacting several crucial factors for leukemia stem cell (LSC) survival, such as c-Myc, β-Catenin, E2f, Ezh2, Alox5, and mTOR. Additionally, Purinostat mesylate enhances glutamate metabolism in LSCs by increasing GLS1.