Butein tetramethyl ether
Product Specifications
CAS Number
155048-06-9
Target
BCRP
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Butein tetramethyl ether (Compound 20) is a potent and selective inhibitor of breast cancer resistance protein / ATP-binding cassette sub-family G member 2 (BCRP/ABCG2) . It inhibits MCF-7 MX and MDCKBCRP cells with IC50 values of 2.2 μM and 1.03 μM, respectively. Butein tetramethyl ether holds potential for cancer research.
Smiles
C(/C=C/C1=CC(OC)=C(OC)C=C1)(=O)C2=C(OC)C=C(OC)C=C2
Molecular Formula
C19H20O5
Molecular Weight
328.359
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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